Textbook of Drug Design and Discovery, now in its 3rd edition, offers a comprehensive and updated overview of the drug development process. The book thoroughly explores every aspect of drug design - from the initial identification of promising leads through the optimization of molecular structures and analysis of structure-activity relationships, to the detailed procedures of clinical evaluation and eventual registration. Designed for students of chemistry, pharmacy, pharmacology, biochemistry, and medicine, this edition provides insight into the development of enzyme inhibitors and the creation of drugs targeting specific cellular components such as ion channels and receptors. It also delves into specialized areas that include peptidomimetics, antivirals, and anticancer agents, while discussing modern methods like gene technology, computer modeling, and combinatorial approaches in pharmaceutical research.
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