Now in its sixth edition, Principles of Gene Manipulation remains an indispensable resource for advanced undergraduates with a solid background in genetics. This seminal textbook offers a comprehensive introduction to the genetic engineering of plants, animals, and microbes, guiding readers through techniques that have reshaped the field over recent years. Substantially updated and thoroughly revised, this edition reflects the rapid advancements in core technologies achieved since its previous version. The final chapter is thoughtfully organized into six themes: nucleic acids as diagnostic tools, innovative drugs and therapies for genetic diseases, strategies to combat infectious disease, protein engineering, metabolic engineering, and modern plant breeding. A complementary website further enriches the learning experience, providing valuable resources alongside emerging chapters on genomics and proteomics.
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