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Principles of Biochemical Toxicology, Fourth Edition, delivers a comprehensive examination of the molecular events that underlie toxic effects, carefully detailing the factors that influence toxicity. Author John A. Timbrell guides readers through core concepts such as dose-response relationships, metabolism, and the body's disposition of foreign compounds, rendering complex mechanisms accessible to students and professionals alike. The updated edition reorganizes content into foundational principles followed by discussions of various toxicity types. Extensive use of real-world examples and numerous explanatory diagrams enhance understanding, while newly added material covers topics including risk assessment, export systems, oxidative stress, and effects related to compounds such as Thalidomide, Tamoxifen, and asbestos proliferators. Each chapter concludes with review questions and model answers, supplemented by expanded bibliographies to support further study. Presented in a clear and concise format with thoroughly revised artwork, this hardcover text stands as an essential resource for anyone seeking a deeper insight into biochemical toxicology.
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